Mass Spectrometry in Cancer Diagnosis

Authors

  • Jan Nedvěd Microbiological Institute, Academy of Sciences of the Czech Republic, Prague
  • Marián Hajdúch Institute of Molecular and Translational Medicine, Faculty of Medicine, Palacký University and Faculty Hospital, Olomouc
  • Karel Lemr Department of Analytical Chemistry, Faculty of Science, Palacký University, Olomouc
  • Vladimír Havlíček Microbiological Institute, Academy of Sciences of the Czech Republic, Prague

Keywords:

tumor marker, mass spectrometry, dynamic range

Abstract

Tumor markers play an important role in cancer diagnostics. However, with the exception of selected fusion genes and proteins, there are no specific compounds for unambiguous cancer diagnosis. Oncologists must combine many markers to assess diagnosis, staging, prognosis and prediction of therapeutic response. Mass spectrometry (MS) is a powerful technique which can help to identify new biomarkers and/or to refine information about marker candidates. Recent years have witnessed new approaches in MS analysis for dicovery of cancer biomarkers. This review highlights some recent findings and trends in cancer diagnosis.

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Published

2011-05-15

How to Cite

Nedvěd, J., Hajdúch, M., Lemr, K., & Havlíček, V. (2011). Mass Spectrometry in Cancer Diagnosis. Chemické Listy, 105(5), 356–360. Retrieved from http://chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1139

Issue

Vol. 105 No. 5 (2011)

Section

Articles