HPLC Determination of Norepinephrine in Pharmaceuticals

Authors

  • Ivana Brabcová Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové
  • Dalibor Šatínský Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové
  • Petr Solich Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové

Keywords:

HPLC, ion-exchange chromatography, noradrenaline, drugs

Abstract

The aim of the work was to develop a new chromatographic method for the determination of norepinephrine in intravenous infusions. The new method is based on separation of norepinephrine and the internal standard paracetamol on a strongly acid cation exchanger. The validation parameters of the method were satisfactory. The method is applicable for the above purpose in routine analysis.

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Published

2011-11-15

How to Cite

Brabcová, I., Šatínský, D., & Solich, P. (2011). HPLC Determination of Norepinephrine in Pharmaceuticals. Chemické Listy, 105(11), 864–868. Retrieved from http://chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1030

Issue

Vol. 105 No. 11 (2011)

Section

Articles

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