3D Lipidic Matrix for Incorporation and Stabilization of Biologically Active Molecules

This article is part of the series Women in Czech Chemistry

Authors

  • Martina Zatloukalová Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic http://orcid.org/0000-0001-5868-8002

DOI:

https://doi.org/10.54779/chl20220172

Keywords:

lipidic nanoparticles, lipidic cubic phase, cubosome, hexosome, biological active compound

Abstract

In aqueous media, biologically active substances are usually unstable, poorly soluble compounds with low bioavailability. Incorporation of these compounds into the structure of lipid-based lyotropic liquid crystalline phase or nanoparticles can increase their solubility and subsequent bioavailability. The aim of this review is to clarify the principle of self-assembly of lipidic amphiphilic molecules in the aqueous environment, to present lipid bicontinuous cubic and hexagonal phases and their current biological application.

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Published

2022-03-15

How to Cite

Zatloukalová, M. (2022). 3D Lipidic Matrix for Incorporation and Stabilization of Biologically Active Molecules: This article is part of the series Women in Czech Chemistry. Chemické Listy, 116(3), 172–179. https://doi.org/10.54779/chl20220172

Issue

Vol. 116 No. 3 (2022)

Section

Articles