Principles of New DNA Sequencing Methods

  • M. Gaplovský Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava,
  • K. Gaplovská-Kyselá Department of Genetics, Faculty of Natural Science, Comenius University, Bratislava

Abstrakt

Recently, a combination of biochemical, chemical, physical and engineering techniques enabled a substantial advancement of determination of primary structure of nucleic acids. New methods emerged that made DNA sequencing faster, less expensive and less labor-consuming. This review describes principles of the current and new sequencing methods as well as indicates directions of future development.
Publikované
2012-10-15
Sekce
Články