Metabolomic Techniques in Biomedicine

  • P. Wojtowicz Laboratory for Inherited Metabolic Disorders and Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc
  • H. Janečková Laboratory for Inherited Metabolic Disorders and Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc
  • D. Friedecký Laboratory for Inherited Metabolic Disorders and Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc
  • T. Adam Laboratory for Inherited Metabolic Disorders and Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc

Abstrakt

Global metabolite profiling, often called metabolo¬mics, is an expanding research field. Together with genomics, transcriptomics and proteomics, it provides additional information on specific changes occurring in biological systems, allowing to better understand metabolic pathways and their pathologies. This review highlights the current metabolomic challenges in biomedicinal research using chromatographic and electrophoretic separation techniques coupled mostly with mass spectrometry. The most frequently used procedures for obtaining bioinformation data are introduced as well.
Publikované
2013-02-15
Sekce
Články