Enantioselective Reductions of Prochiral Ketones by Means of Oxazaborolidines

Autoři

  • M. Taraba* *Spolana, ZKCH, Neratovice, **Department of Organic Chemistry, Institute of Chemical Technology, Prague
  • J. Palecek** *Spolana, ZKCH, Neratovice, **Department of Organic Chemistry, Institute of Chemical Technology, Prague

Abstrakt

The possibilities of synthetic utilization of enantioselective reductions of prochiral ketones catalyzed by 1,2,3-oxazaborolidines are shown on a series of representative pattern reactions. The presented reactions are evaluated from the point of view of reaction conditions, i.e. type and amount of the used catalyst, reduction agent (BH3.THF, BH3.SMe3, catecholborane), solvent (THF, toluene, CH2Cl2, i.a.) or activator (simple alcohols or ethanolamine).

Stahování

Publikováno

15.02.1997

Jak citovat

Taraba*, M., & Palecek**, J. (1997). Enantioselective Reductions of Prochiral Ketones by Means of Oxazaborolidines. Chemické Listy, 91(1). Získáno z http://chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/2802

Číslo

Vol 91 No 1 (1997)

Sekce

Články