HPLC Determination of Paracetamol in Human Serum

  • D. Prochazkova* *Institute of Clinical and Experimental Medicine, Prague, **Institute of Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague
  • P. Drasar** *Institute of Clinical and Experimental Medicine, Prague, **Institute of Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague
  • J. Vacha* *Institute of Clinical and Experimental Medicine, Prague, **Institute of Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague

Abstrakt

A simple method was developed for measuring tha paracetamol concentration in human serum by reversed-phase HPLC. The suggested method is sufficiently precise, sensitive, and selective. The time of proper analysis does not exceed 15 min. The linear response of the detector has been proved for the range of 1-80 mg.l-1 paracetamol.
Publikované
1997-06-15
Sekce
Články