Proteomics in Molecular Toxicology: Identification of Potential Early Protein Biomarkers for Hepatocarcinogenicity in Rats

Autoři

  • K. Fella Merck KGaA, Institute of Toxicology,
  • M. Glückmann Applied Biosystems, Darmstadt, Germany
  • V. Kruft Applied Biosystems, Darmstadt, Germany
  • P.-J. Kramer Merck KGaA, Institute of Toxicology,
  • M. Kröger Merck KGaA, Institute of Toxicology,

Abstrakt

Modern proteomics technology was used for identification of protein biomarkers for hepatocarcinogenicity. It replaced currently used methods for the studies of toxic effects of drug candidates. The detection of new biomolecular markers can shorten future studies.

Publikováno

15.01.2006

Jak citovat

Fella, K., Glückmann, M., Kruft, V., Kramer, P.-J., & Kröger, M. (2006). Proteomics in Molecular Toxicology: Identification of Potential Early Protein Biomarkers for Hepatocarcinogenicity in Rats. Chemické Listy, 99(12). Získáno z http://chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1974

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