Separation of Quaternary Benzo[c]phenanthridine Alkaloids from Macleaya cordata

Autoři

  • J. Vičar Institute of Mediincal Chemistry and Biochemistry,
  • M. Soural Department of Organic Chemistry, Palacký University, Olomouc
  • J. Hlaváč Department of Organic Chemistry, Palacký University, Olomouc

Abstrakt

A cost-effective method for separation of sanguinarine and chelerythrine from commercial Macleaya cordata extract (sanguiritrin) is described. In the first step, the alkaloids are reduced with NaBH4 to dihydro derivatives, which are easily separated by column chromatography on silica gel with chloroform and chloroform-methanol elution. In the second step, the dihydro derivatives are photochemically oxidized to the title alkaloids.

Stahování

Publikováno

15.02.2010

Jak citovat

Vičar, J., Soural, M., & Hlaváč, J. (2010). Separation of Quaternary Benzo[c]phenanthridine Alkaloids from Macleaya cordata. Chemické Listy, 104(1). Získáno z http://chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1420

Číslo

Vol 104 No 1 (2010)

Sekce

Články