History and Significance of Chiral Analysis of Amino Acids in Biological Matrices and Environment

Page: 703

H. Zahradníčkováa,c, P. Hartvicha,b, and I. Holoubekc

a Laboratory of Analytical Biochemistry, Institute of Entomology, Academy of Sciences of the Czech Republic, 370 05 České Budějovice, b Department of Organic and Nuclear Chemistry, Faculty of Science, Charles University, 128 43 Prague 2, Czech Republic, c Recetox, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic


The review deals with the history and significance of chiral analysis of amino acids in physiological matrices, food and environment including the outer space since the 1930´s. The review discusses the importance of D-amino acids for formation and differentiation of cells or tissues, for biological and geological dating and the origin of life on Earth and diagnostical value of D-amino acids in food control and clinical biochemistry.


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