Gibberellins, Antheridiogens and Incrustoporins: A Personal Account of Syntheses of Small, Highly Functionalized Molecules
Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Hradec Kralove
A description of author´s achievements in the synthesis of natural products and their analogues, including partial syntheses of plant hormones gibberellins and antheridiogens, total syntheses of marine natural products nakienones A and B, and the preparation of analogues of a butenolide secondary metabolite, (-)-incrustoporin. Both classic and modern synthetic chemistry methods were employed; at that, undesirable reactivity was encountered, especially when highly reactive functionalities had to be accommodated on a relatively small matrix.
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