Molecular Recognition with Novel Chromatographic Phases Based on Combination of Porphyrins and Expanded Porphyrins with Chiral Binaphthyl Derivatives: Application for the Separation of Biologically Important Substrates

Page: 147

I. Kavenova *, R. Holakovsky **, M. Hovorka **, V. Kriz *, P. Anzenbacher Jr. *, P. Matejka *, V. Kral *, J. W. Genge ***, and J. L. Sessler ***

* Department of Analytical Chemistry,** Department of Organic Chemistry, Institute of Chemical Technology, Prague; *** Department of Organic Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, USA


A novel possibility for the chiral separation mode based on multiple recognition by mixed macrocycle-binaphthyl ligands on derivatized aminopropylsilica gel HPLC sorbents is presented. These novel chromatographic sorbents showed a great potential for aminoacid and saccharide separations.


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