Radiopharmaceuticals for Diagnostics and Therapy of Neuroendocrine Tumors
Institute of Macromolecular Chemistry, AS CR, v.v.i., Prague
Keywords: neuroendocrine tumors, radiopharmaceuticals, somatostatin, fluorodeoxyglucose, m-iodobenzylguanidine, fluorodihydroxyphenylalanine, 5-hydroxytryptophan; exendin
This article provides a general overview of radiopharmaceuticals for diagnostics and therapy of neuroendocrine tumors. These agents employ specific differences between neuroendocrine tumors and normal tissues on the cellular level. Individual radiopharmaceuticals demonstrate examples of typical strategies for targeted radionuclide accumulation in tumor cells.
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