Nature-Inspired Stimuli-Responsive Polymers for Drug Delivery

Page: 482

M. Hrubý, S. K. Filippov, V. Felklová, and P. Štěpánek

Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Prague

Keywords: stimuli-responsive polymers, pH-responsivity, redox responsivity, targeted delivery and controlled release

 

The review introduces potential advantages and limitations of applications of stimuli-responsive polymers for delivery of drugs, radionuclides and genes. Special emphasis is put on pH- and redox-responsive systems. Virus-inspired systems combining pH-responsivity and reductive degradability are especially promising in the delivery of substances bioactive in the cells.

 

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