Extraction-Spectrophotometric Determination of Fentanyl and Its Derivatives

Page: 135

R. Jelínková, E. Halámek, and Z. Kobliha

NBC, University of Defence, Vyškov, Czech Republic

Keywords: fentanyl and derivatives, UV/VIS spectrophotometry, extraction, azo-dye


Methods of determination of fentanyl, alfentanil, re¬mifentanil and sufentanil were developed based on their ability to form coloured associates with acid dyes which can be extracted chloroform. Crocein Orange and Amido Black dyes produce the 1:1 and 2:1 associates at 485 nm and 626 nm, respectively.


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