Separation of Enantiomers of Proteinogenic Amino Acids on Teicoplanin Stationary Phases

Page: 436

Z. Deákováa,b, Z. Ďuračkováb, and J. Lehotaya

a Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, b Institute of Medicinal Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic

 

Macrocyclic glycopeptides are becoming popular in chiral analytical chemistry due to a wide spectrum of their applications. Teicoplanin columns provide a highest separation selectivity of amino acid enantiomers, especially of underivatized amino acids. Chiral stationary phases can be also used for determination of amino acid enantiomers in biological samples.

 

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