Traditional Tablet Fillers as Nanocarriers of Drugs
Department of Pharmaceutical Technology, Faculty of Pharmacy, Charles University, Hradec Králové
Clay minerals such as talc, bentonite or kaolin have been used as pharmaceutical excipients for quite a long time. Recently, small size and interesting structure of their components such as montmorillonite and halloysite or newly discovered imogolite, became interesting as inexpensive and environment-friendly nanomaterials. In addition to their use in industry, they seem to be promising drug nanocarriers. The present review describes the recent research of their utilization in controlled drug release and outlines their potential use as biocompatible materials in medicine and tissue engineering.
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