Metabolomic Techniques in Biomedicine

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P. Wojtowicz, H. Janečková, D. Friedecký, and T. Adam

Laboratory for Inherited Metabolic Disorders and Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc


Global metabolite profiling, often called metabolo¬mics, is an expanding research field. Together with genomics, transcriptomics and proteomics, it provides additional information on specific changes occurring in biological systems, allowing to better understand metabolic pathways and their pathologies. This review highlights the current metabolomic challenges in biomedicinal research using chromatographic and electrophoretic separation techniques coupled mostly with mass spectrometry. The most frequently used procedures for obtaining bioinformation data are introduced as well.


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