Principles of New DNA Sequencing Methods

Page: 809

M. Gaplovskýa and K. Gaplovská-Kyseláb

a Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava, b Department of Genetics, Faculty of Natural Science, Comenius University, Bratislava


Recently, a combination of biochemical, chemical, physical and engineering techniques enabled a substantial advancement of determination of primary structure of nucleic acids. New methods emerged that made DNA sequencing faster, less expensive and less labor-consuming. This review describes principles of the current and new sequencing methods as well as indicates directions of future development.


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