Cell Proliferation on a Conducting Polymer (Polyaniline)

Page: 380

P. Humpolíčeka,b, V. Kašpárkováa,c, J. Stejskald, Z. Kucekováa,b, and P. Ševčíkovác

a Centre of Polymer Systems, b Polymer Centre, c Department of Fat, Surfactans and Cosmetics Technologies, Faculty of Technology, Tomas Bata University, Zlín, d Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Prague


Polyaniline (PANI) belongs to a group of conducting polymers that show numerous properties useful in biome¬dical applications. Although PANI has long been studied in terms of interaction with human tissue, the published studies are mostly focused on composites of polyaniline with other polymers, not allowing for generalization of the obtained results. The present study is focused on the adhe¬sion of human liver cells to a conducting and non-conducting polyaniline films. The ability of human liver cells to attach to both types of the tested surfaces was con¬firmed. Cell proliferation on the PANI surfaces was moni¬tored in relation to material biocompatibility and to its practical applications. The results showed statistically sig¬nificant differences in cell proliferation depending on the type of PANI film. The study thus points out the need to test materials in their neat forms, which allow for better generalization of the test results leading to their broader applications.


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