Optimization of Solid-Phase Extraction of Selected Non-Steroidal Anti-inflammatory Drugs by Capillary Zone Electrophoresis

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L. Čapka, P. Lacina, and M. Vávrová

Institute of Chemistry and Technology of Environmetal Protection, Faculty of Chemistry, University of Technology, Brno


This study is focused on the development of solid-phase extraction (SPE) of some acid drug residues from water environment. The target drugs are non-steroidal anti-inflammatory drugs - salicylic acid, diclophenac, ibuprophen, ketoprophen, naproxen and acetaminophen. The extraction efficiency of SPE was evaluated by capillary zone electrophoresis of the above drugs in SPE effluents. Methods are developed for determination of residues of selected drugs and similar compounds in real samples of water.


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