Biologically Active Compounds Immobilized on Magnetic Carriers and Their Utilization in Biochemistry and Biotechnology

Page: 524

M. Pečováa, L. Zajoncováa, K. Polákováb, J. Čudab , M. Šafaříkovác, M. Šebelaa, and I. Šafaříkb,c

a Department of Biochemistry, Faculty of Science, Palacký University, Olomouc, b Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacký University, Olomouc, c Department of Nanobiotechnology, Institute of Systemic Biology and Ecology, Academy of Sciences of the Czech Republic, České Budějovice


Magnetic microparticles and nanoparticles, composed mainly of iron oxides (magnetite, Fe3O4 and maghemite, γ-Fe2O3), can be utilized in various biochemical and biotechnological applications. The particles can be easily manipulated by an external magnetic field. They are frequently used as magnetically responsive insoluble supports for immobilization of biologically active compounds, such as enzymes, antibodies, streptavidin and oligonucleotides. Examples of their applications are presented.


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