HPLC Determination of Norepinephrine in Pharmaceuticals

Page: 864

I. Brabcová, D. Šatínský, and P. Solich

Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové


The aim of the work was to develop a new chromatographic method for the determination of norepinephrine in intravenous infusions. The new method is based on separation of norepinephrine and the internal standard paracetamol on a strongly acid cation exchanger. The validation parameters of the method were satisfactory. The method is applicable for the above purpose in routine analysis.


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