Mass Spectrometry with Negative Chemical Ionization and Its Utilization in GC-MS Analysis of Organic Pollutants

Page: 913

R. Húšková, E. Matisová, and S. Hrouzková

Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic


Mass spectrometry as a detection method has been widely used in various fields of chemistry. Negative chemical ionization (NCI), one of the techniques used in MS, is based on interactions between anions of a reagent gas (frequently methane) and analyte molecules. When coupled to GC, the technique is used in analysis of organic pollutants. The development of analytical methods appropriate for various complex matrices, selective to the analytes at very low concentrations is still needed. The review with 40 references shows the potentials of GC-NCI-MS in analytical practice.


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