The Levels of Organochlorine Pesticides in Follicular Fluid of Infertile Women

Page: 589

S. Jirsováa, J. Mašataa, L. Jechb, P. Drbohlavc, M. Jaržembovskáa, J. Pavelkováa, M. Moosováa, K. Řežábeka, V. Benckod, and J. Zvárováe

a Clinics of Gynecology and Obstetrics, First Faculty of Medicine, Charles University and General Teaching Hospital, Prague, b Axys Varilab Co., Vrané nad Vltavou, c Pronatal Spa Institute, Karlovy Vary, d Department of Hygiene and Epidemiology, First Faculty of Medicine, Charles University, Prague, e EuroMISE Centre, Prague and Institute of Information Science, Academy of Sciences of the Czech Republic, Prague

 

The aim of this study was to detect DDT and its metabolites, 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene (DDE) and 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (DDD), in blood and follicular fluid of infertile women undergoing in vitro fertilization and the embryo transfer program. The accumulation of DDT, DDE and DDD in follicular fluid of 30 infertile women was confirmed. The concentrations of the compounds in blood were 1.7 - 5985 in follicular fluid and 3.5 - 35 229 ng/g fat, respectively.

 

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