Cycle of Sodium Ions in Bacteria and Methanoarchaea
Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences, Ivanka pri Dunaji, Slovak Republic
This review discusses the progress of bioenergetic studies on the role of Na+ in bacteria and Archaea. Na+ ions have at least four functions in bacterial and Archaeal cells, namely in the Na+- ion X cotransport system, Na+-coupled energy transformation, pH homeostasis mechanisms, and activation of special enzymes. Thus, in a number of bacteria and Archaea, endergonic and the exergonic membrane-associated processes are linked by the cycling of Na+ ions which shows that Na+, under certain conditions, can substitute H+ as the coupling ions. This review also discusses some problems related to the Na+ cycle in human pathogens.
Full text (PDF)