Study of Synthesis of 3'-Deoxy-3'-[18F]fluorothymidine – Prospective Radiopharmaceutical in Positron Emission Tomography

Page: 992

L. Procházka, M. Kropáček, M. Mirzajevová, J. Zimová, M. Försterová, H. Švecová, and F. Melichar

Nuclear Physics Institute, Academy of Sciences of the Czech Republic, Řež near Prague


18F-Labelled compounds as active substances of radiopharmaceuticals are used for imaging in positron emission tomography (PET) in nuclear medicine. The radiosynthesis of PET radiopharmaceuticals is based on nucleophilic substitution with F? in a precursor. The synthesis is demonstrated on 3'-deoxy-3'-[18F]fluorothymidine.


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