Methods of Study of Protein - Protein Interactions

Page: 28

M. Wildová and M. Rumlová

Gilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic


The knowledge of the pattern and mechanism of protein - protein interactions helps in elucidation, on the molecular basis, of functioning of living organisms as well as in understanding cellular processes and functions. This review summarizes the widely used biochemical methods, from the oldest (but still powerful) to the most recent techniques, for identification and characterization of novel protein - protein interactions.


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